Peptiva 15 Day Review: Better Gut Health & Restful Sleep All-In-one

We’ve all dealt with digestive issues, but for some of us, it’s a chronic problem. We feel sick or uncomfortable after we eat. And we’re not as regular as we want to be. After a while, it starts affecting your daily life.

I’ve avoided dinners with friends because I was afraid that I’d feel bloated or have to run to the bathroom. What kind of life is that?

If you’re like me, your digestive issues probably stem from one thing: an unhealthy diet. And it’s probably destroyed your good gut bacteria.

You’re probably well aware of the benefits of probiotics and how they can help restore good gut bacteria. But to see real results, you’ll need to do more than eat a cup of yogurt per day.

There are plenty of probiotic supplements out there, but Peptiva offers something a little extra: a good night’s sleep.

What is Peptiva?

what is peptiva?

Peptiva is a probiotic that you take at night. The goal is to heal your gut while you sleep.

Why take probiotics at night?

Because that’s when your digestive system is least active. Because your digestive system isn’t busy breaking down food, the probiotics can work their magic and help replenish good gut bacteria.

Think about it – most people take probiotics first thing in the morning, and then dump all of this bad food into their bodies throughout the day. Essentially, they’re killing the good bacteria before it even has a chance to reproduce in their guts. This is the theory behind Peptiva’s probiotic supplement, and it makes a lot of sense.

We know that studies show that nighttime is the best time to take prebiotics but there’s a difference between theory and practice (more on that soon).

Along with a proprietary Probiotic Matrix, Peptiva also includes other ingredients that are supposed to promote restful sleep.

Who Makes It?

Dr. David L. Katz

Peptiva is doctor-formulated, created by Dr. David L. Katz.

Dr. Katz is the director and co-founder of the Yale Prevention Research Center, and he’s also the director of Integrative Medicine at Griffin Hospital.

Peptiva itself is owned by GNC, and their products are manufactured at a facility in the UK.

The facility uses a patented freeze-drying method to lock in the stability of the probiotics.  For 2018, it was the best selling probiotic for all GNC.

peptiva gnc

Peptiva Ingredients

Peptiva Ingredients - Best Probiotics Comparison

Let’s get down to business and talk about the most important thing: ingredients. Peptiva actually contains a wide range of ingredients, including:

Active Microbiome Blend (Part of the Probiotic Matrix)

The Active Microbiome Blend includes two strains of probiotics:

Lactobacillus rhamnosus

  1. Rhamnosus has been shown to help in the prevention and treatment of diarrhea and gastrointestinal infections. It can reduce the duration of diarrhea and reduce the risk of developing gastrointestinal infections.

It has even been effective at treating stress-induced intestinal dysmotility in rodents.

It helps fight viruses, parasites and bacteria, and can even help improve your immune system.

Lactobacillus paracasei

  1. Paracasei exhibits antibacterial properties and can also help with allergies and inflammation.

But most importantly, this strain of bacteria has been shown to increase the number of Bifidobacteria and Lactobacilli in humans. It can also strengthen the intestinal barrier.

It alleviates constipation and resolves diarrhea.

Lab4 Clinical Cultures (Part of the Probiotic Matrix)

The Lab4 Clinical Cultures blend contains a wider range of bacteria strains, including:

Lactobacillus acidophilus

  1. acidophilus has been shown to improve intestinal microbiota. In one study, volunteers who took the strain showed increased levels of Bifidobacteria, Lactobacilli, Eubacterium and Collinsella.

It also counteracts inflammation in the gut and boosts immunity.

Bifidobacterium animalis subsp lactis

  1. Animalis ssp lactis has been shown to:

Bifidobacterium bifidum

  1. Bifidum can reduce irritable bowel syndrome, pathogen infections and diarrhea. It’s been shown to fight stress and even provide antioxidant properties.

Intake of this bacteria strain has been shown to improve the microbiota of the intestinal tract of mice.


Melatonin is a well-known sleep aid, and it works by controlling the body’s circadian rhythm.

There are two types of melatonin in this product: immediate and delayed release.

The immediate form is supposed to help you feel tired and fall asleep more quickly. The delayed form is supposed to promote a deeper and more restful night of sleep.


GABA is actually produced through the fermentation of lactobacillus. It promotes a calm state of mind, eases stress, promotes relaxation and enhances sleep.

Studies have shown that GABA can increase alpha waves, which are generated when you’re relaxing, and decrease beta waves, which are generated during highly stressful situations.

GABA can even normalize urinary patterns that can disrupt your sleep.

Valerian Root Extract

Valerian root is a medicinal herb derived from the Valeriana officinalis plant that has been in use since the time of the ancient Greeks and Romans. The plant also promotes relaxation and a deeper, more restorative sleep.

Does Peptiva Really Work?

does the peptiva sample work

Peptiva’s ingredient list looks promising, but does this probiotic really improve digestion while promoting better sleep?

If you take a look at Peptiva reviews, you’ll see that most of them are positive. Some people complain that Peptiva doesn’t make them fall asleep faster or stay asleep. But most report having better digestive health – and that’s really the most important thing.

Remember that Peptiva isn’t designed to be a sleep aid; it’s designed to improve your digestive health.

The product contains all of the well-known strains of probiotics that have been shown to replenish good gut bacteria. It may take a week or two to really start seeing results, but most people who have tried and reviewed the product say that it improves their digestive issues.

The only concern is that the product doesn’t have to be refrigerated, but the freeze-drying process is supposed to keep the probiotics intact.

The only way to know if Peptiva will work for you is to give it a try for yourself. But maybe you don’t want to fork over the cash for a product you don’t know will work.

Here’s the good news: You can now buy Peptiva directly from Amazon.